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February 1960

A Comparative Analysis of Two Procedures for Chronic Duodenal Ulcer: Antrectomy with Vagectomy or Partial Gastrectomy with Vagectomy

Author Affiliations

Des Moines, Iowa
From the Department of Surgery, Veterans Administration Hospital.

AMA Arch Surg. 1960;80(2):253-257. doi:10.1001/archsurg.1960.01290190073014

Introduction  A comparative evaluation of our results with two procedures—antrectomy with vagectomy and partial gastrectomy with vagectomy—provides us with the data that are necessary in selecting the operative procedure to be used in future cases. In the quest for the development of the ideal operation for duodenal ulcer, application of the currently known physiologic principles of gastric digestion and abnormal functions is paramount. In view of the many recent studies concerning the neurogenic phase and antral stimulatory control of gastric secretion and digestive function, it appeared logical that abolition of these two functions might provide the ideal operative procedure which would result in the least desirable physiologic sequelae. Because of this, a limited gastric resection was combined with a vagectomy.

Purpose  The purpose of this survey is to present our results, in a comparative manner of the two procedures, antrectomy with vagectomy (A-V) and partial gastrectomy with vagectomy (P-V). The

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