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July 1960

Systematic Clearance of Intestinal Polyps for Hemorrhage in Peutz-Jegher's Syndrome: Report of a Case

Author Affiliations

Spokane, Wash.

Arch Surg. 1960;81(1):87-89. doi:10.1001/archsurg.1960.01300010089016

The syndrome of small intestinal polyposis associated with melanin spots of the oral mucosa, lips, and digits was first described in 1921 by Peutz1 in Holland. A comprehensive report of 10 cases by Jegher and associates2 in 1949 has been followed by a number of separate reports. Because of the rarity of this syndrome and the successful treatment of the present case, it is considered worth while to present this report with some pertinent facts relative to the origin, diagnosis, and treatment utilized.

Characteristically, the incidence of freckle-like spots in and about the mouth may be associated with one or many polyps of the small intestine. The polyp tendency may be present in the stomach or colon and less frequently in the urinary bladder, bronchi, or nares. Clinical manifestations of the disease are hemorrhage and intussusception rather than the frequency of malignant change that occurs in familial colonic

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