[Skip to Navigation]
February 1961

Bilateral Superior Cervical Sympathectomy: Effect on Cerebral Blood Flow of Normal Dogs

Author Affiliations

From the Surgical Research Laboratory, U.S. Veterans Hospital, Perry Point, Md.

Arch Surg. 1961;82(2):308-313. doi:10.1001/archsurg.1961.01300080136012

The purposes of this paper are to compare the data obtained by a study of the cerebral blood flow of normal dogs measured by Kety's method before and at an average of six months after a bilateral superior cervical sympathetic ganglionectomy.

This work originated six years ago when one of us planned a carotid endarterectomy for arteriosclerotic occlusion and found the internal carotid artery occlusion was both extracranial and intracranial, preventing its removal. Convinced of the beneficial effect of lumbar sympathectomy in arterial occlusive disease of the lower extremities, the literature of the effect of superior cervical sympathetic ganglionectomy on the cerebral circulation was reviewed.

Literature of Subject  The experimental articles that seemed to us to be the most pertinent and significant were the following:1. In 1858 Claude Bernard3 observed that in dogs a unilateral superior cervical sympathetic ganglionectomy caused an increase in the temperature of the brain