[Skip to Content]
[Skip to Content Landing]
June 1961

Primary Hyperaldosteronism and Related Hypertension: Surgical Management

Author Affiliations

From the Division of Surgery, Marquette University School of Medicine, and the Department of Surgery, Milwaukee County Hospital.

Arch Surg. 1961;82(6):888-903. doi:10.1001/archsurg.1961.01300120102012

The recognition by Conn1 in 1955 that certain adenomas of the adrenal cortex secrete excessive amounts of aldosterone associated not only with electrolyte disturbances and altered renal function but also with a severe and formerly fatal hypertension has given a new emphasis to the importance of endocrinopathies to physicians and surgeons alike. The syndrome of primary hyperaldosteronism is not rare; on the contrary, Conn2 states that he has knowledge of approximately 150 such cases. Not all of these cases have been reported, and of these that have, the vast majority appear in the nonsurgical literature. This seems regrettable since the definitive treatment of this disease is surgical. We have reviewed 27 cases reported in adequate detail to allow study from a surgical point of view and have added 3 from our own experience of the last year, numbers 4-23 (Table 1).

Report of Cases 

Case 1.  —A 39-year-old