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June 1961

Rhabdomyosarcomas in Childhood: A Review of 14 Cases

Author Affiliations

From the Departments of Surgery and Pathology, The Children's Hospital.

Arch Surg. 1961;82(6):943-949. doi:10.1001/archsurg.1961.01300120157018

Introduction  Although the rhabdomyosarcomas are rare in adults, these tumors occur with some frequency among children. Over the past 15 years at the Columbus Children's Hospital, 310 solid malignant tumors have been entered in the hospital's Tumor Registry. This represents an unselected series of tumors seen in a general children's hospital. Excluding the tumors of the central nervous system, rhabdomyosarcomas were exceeded in number only by the neuroblastomas and Wilms' tumors. This paper discusses our experience with 14 cases of rhabdomyosarcoma of various types and locations (Table 1).

Classification  Our cases of rhabdomyosarcoma have been classified according to the histological scheme advocated by Horn and Enterline.1 According to this system, the 3 types are: (1) the pleomorphic, found primarily in adults; (2) the alveolar, which appears largely in adolescents and young adults, and (3) the embryonal, which occurs mainly in infants and children. It is now fairly well accepted