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March 1962

Starch Powder Granulomas in the Peritoneal Cavity

Author Affiliations

Senior Resident (Dr. Webb), and Chief of Surgery (Dr. Regan), Queen of Angels Hospital.

Arch Surg. 1962;84(3):282-285. doi:10.1001/archsurg.1962.01300210016003

During recent years, case reports of starch granulomas have been appearing with increasing frequency. It is the purpose of this paper to present 3 illustrative cases. to discuss the diagnostic problems created by starch granulomas in the peritoneal cavity, and to alert the surgeon to this iatrogenic disease which increases surgical morbidity and mortality.

Almost 30 years ago Antopol reported that talc is capable of producing granulomas in living tissue. As the case reports of talc granulomas increased, an intensive search for an absorbable, nonreactive glove powder was instituted and supposedly consummated with a specially prepared starch powder. An investigative report in 1947 told of the tissues' apparently complete absorption of this specially prepared starch powder,1 but this thesis was modified by Lee and his co-workers in a 1952 reappraisal of the so-called "absorbable" powder.2 The following reports are clinical demonstrations of the effect of starch glove powder

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