The relative rarity of tumors of the vermiform appendix is well-established, for these lesions constitute less than 0.5% of all gastrointestinal neoplasms.1 The incidence of neoplastic disease found in surgically removed appendices is also quite small, being reported in several large series as 0.35% to 0.38%.2 Of the tumors of the appendix, the vast majority are malignant or are generally considered so. There are 3 well-defined histological types of appendiceal malignancy, namely, carcinoid, malignant mucocele, and adenocarcinoma.3 The reported relative incidence of these types varies, but all writers agree that carcinoid tumors are by far the most common, comprising 89% to 93% in several series of reported cases. Malignant mucoceles, called by some "cystic carcinomas," account for approximately 8% of appendiceal cancer.4 Primary adenocarcinoma of the appendix in most reported series accounts for less than 0.4% of all appendiceal malignancies, but the incidence varies widely due
DALTON ML. Primary Adenocarcinoma of the Appendix: Report of an Unusual Case of Appendiceal Malignancy. Arch Surg. 1962;84(3):318–321. doi:10.1001/archsurg.1962.01300210052010
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