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June 1962

Coronary Insufficiency: Correction by Internal Mammary Ligation

Author Affiliations

Department of Research of Timken Mercy Hospital.

Arch Surg. 1962;84(6):674-676. doi:10.1001/archsurg.1962.01300240078012

A number of surgical operations have been devised during the past 20 years for increasing blood supply to the myocardium.1 Many investigations have been performed in this field, either as experimental work on animals or as clinical studies.2 Some have claimed improvement in the clinical studies following internal mammary artery ligation.1,2 However, many workers in the field have not found improvement.3,4 The present experiments were carried out in an attempt to determine the effect of internal mammary ligation upon mortality of coronary ligation and coronary sinus return in dogs.

Material and Method 

Trial 1. Internal Mammary Ligation.  —Adult dogs of various breeds were used. They were divided evenly into 2 groups, the control and the treated groups. The control animals had their coronary arteries ligated without the preliminary ligation of internal mammary artery, while the treated ones had their internal mammary arteries ligated extrapleurally 3 weeks