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September 1962

Replacement of Main Pulmonary Artery: Experiments in Dogs

Author Affiliations

From the Clinic of Surgery, National Heart Institute.

Arch Surg. 1962;85(3):399-403. doi:10.1001/archsurg.1962.01310030047008

Relief of right ventricular obstruction in tetralogy of Fallot often requires, in addition to infundibular resection, the insertion of an outflow-tract prosthesis. In certain instances correction of such malformations necessitates enlargement of the pulmonary artery by extension of a diamond-shaped right ventricular patch across the pulmonic valve ring for a considerable distance into this vessel. More severe pulmonary artery hypoplasia and varieties of persistent truncus arteriosus may be amenable to correction only if the main pulmonary artery is completely replaced by some type of graft. The results of experiments in which a vascular prosthesis was inserted between the right ventricle and a branch of the pulmonary artery have been reported previously.1 A description of the technique and hemodynamic consequences attending replacement of the main pulmonary artery with a valveless graft comprise the subject of the present report.

Method  Adult mongrel dogs weighing 10 kg. to 16 kg. were anesthetized

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