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November 1962

Blood Pressure Control During Surgical ProceduresNew Possibilities with Administration of Angiotensin

Arch Surg. 1962;85(5):725-729. doi:10.1001/archsurg.1962.01310050027006

The increasing use of surgical procedures on the heart and vascular system make it imperative that the surgeon learn to maintain adequate and accurate control of the blood pressure. It is fundamental to vascular dynamics that an adequate normal blood pressure depends upon accurate adaptation of the vascular bed to the blood volume and stroke volume of the heart. Control of blood pressure seems to be the ideal prophylactic measure against shock in patients who, by the very nature of their myocardial disease, are often unable to maintain adequate systemic pressure. In instances of a diseased myocardium or a fixed stroke output, the reduction of the vascular bed with pharmacological assistance may often be important in maintenance of adequate blood pressure, and, therefore, of perfusion pressure to all areas of the body.

The purpose of this paper is to report my personal experience with the use of a new pressor

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