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January 1963

Coronary Artery Patch Graft: Experiment with Cardiopulmonary Bypass and Hypothermia

Author Affiliations

From the Department of Surgery, School of Medicine University of Kentucky.

Arch Surg. 1963;86(1):81-86. doi:10.1001/archsurg.1963.01310070083011

Introduction  Coronary endarterectomy for occlusive disease has thus far been successfully performed in only a few patients.1,2 The endarterectomy has usually been done with the heart beating normally, after which the coronary arteriotomy has been closed by direct suture. Operations on the left coronary have had a high mortality rate, partly from the location of the left coronary artery which requires much displacement of the heart for operative exposure. Most of the good results have been with the right coronary. Unfortunately, some patients with an initial success after operation have subsequently thrombosed the endarterectomized vessel, a complication similarly seen after endarterectomy of other small arteries. In an attempt to avoid this late occlusion, several investigators have evaluated closure of the coronary artery incision with different types of patch grafts, but none have been uniformly satisfactory.3,4,5 Because of these current problems with coronary endarterectomy, the experiments described in this

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