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February 1963

Cholelithiasis in a Child with Sickle Cell AnemiaCase Report and Review

Arch Surg. 1963;86(2):203-208. doi:10.1001/archsurg.1963.01310080027007

In most of the recorded cases of gall stones in children no mention is made of the associated condition of sickle cell anemia. Its co-existence may have been present in numerous instances. Gibson, in 1722, first recorded a case of gall stones found at autopsy in a 12-year-old boy.5 Herrick7 has received credit for the first description of sickle cell anemia.

Ulin, Nosal, and Martin,18 Glenn and Hill6 and Potter14 have extensively reviewed cholelithiasis and cholecystitis in the child. The 2 former excluded all congenital hemolytic anemias. Potter made no mention of sickle cell anemia associated with any of the 306 cases of cholelithiasis from all causes in the child. Thus, gall stones in the Pediatric age group are rare. Walters, according to Ulin, et al.,18 reported a total incidence of cholelithiasis in children of 1.3 per 1,000 adult cases at the Mayo Clinic.

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