This is a case report of a patient with chondrosarcoma-like tumor of the soft tissues developing in an area of radiation dermatitis five years after external cobalt60 radiotherapy for bronchogenic carcinoma. A similar case diagnosed as osteogenic sarcoma was reported in 1951.3 Recently, lesions histologically resembling those in the case to be presented were reported as sarcoma-like tumors.23
Extraskeletal chondrosarcomas are very rare. The first case reports appeared in the literature in 194333 and 1953.27 Other cases have been reported recently.28,30 Upon the discovery of x-rays in 1895, soft tissue sarcomas following local irradiation were noted as early as 1904.20 In 1909 Coenen stated (cited by Jones14) that 12% of tumors after x-ray treatment were sarcomas. Most authors since then have indicated that squamous cell carcinoma is the main tumor developing after local external radiation.4,5,7,15,31,32 Conversely, sarcomas have been found usually
BRENNER RW, GARRET R. Soft Tissue Chondrosarcoma-Like Tumor: Tumor Arising in an Area of Radiation Injury. Arch Surg. 1963;86(3):471–476. doi:10.1001/archsurg.1963.01310090121022
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