[Skip to Navigation]
Sign In
July 1963

Hereditary Pancreatitis: The Role of Surgical Intervention

Author Affiliations


Arch Surg. 1963;87(1):70-80. doi:10.1001/archsurg.1963.01310130072010

The occurrence of hereditary pancreatitis was first suspected by Comfort and Steinberg5 in 1952. They reported the appearance of chronic relapsing pancreatitis in four members of a single family, possibly affecting two others. Since that report, an additional four kindreds with hereditary pancreatitis have been reported.7,8,10 Several other families have been studied in which the evidence is suggestive that hereditary pancreatitis is present.8,12 In the five kindreds reported to date, 22 definite pancreatitis cases have been detected along with 16 suspected cases. We have studied an additional kindred with hereditary pancreatitis.

The clinical course of this disease is similar to that of the usual variety of chronic relapsing pancreatitis. Recurrent episodes of pancreatitis occur at varying intervals, with the onset of the usual sequelae of chronic pancreatitis as the disease pursues its course. Pancreatic calcifications have been observed in approximately half.12 These calcifications are usually in

Add or change institution