Atherosclerosis is a generalized disease of the arterial system. The localization of atherosclerotic lesions is of importance to the surgeon, as it determines the site and mode of direct surgical attack. It is also of significance in the natural history and prognosis of this disease.
The distribution of atherosclerotic lesions in the arterial tree is also of theoretical interest. A predilection for certain sites would suggest that local factors are relevant to the more general problem of the pathogenesis of atherosclerosis.
This study was undertaken to investigate the localization of atheromatous deposits in certain parts of the arterial system. Definite, frequently recurring patterns of atherosclerosis were found in the arteries to the lower limbs, and the clinical implications are noted. Some conclusions are drawn concerning mechanical factors in atheroma production, and these will be discussed subsequently.
Material and Methods
An analysis of 205 arteriograms of patients with varying degrees of
SINGER A. Segmental Distribution of Peripheral Atherosclerosis. Arch Surg. 1963;87(3):384–390. doi:10.1001/archsurg.1963.01310150020005
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: