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December 1963

Laboratory Findings in Massively Bleeding Gastroduodenal Ulcers: A Review of 2,008 Cases

Author Affiliations

From the Departments of Surgery of the Cook County Hospital, Northwestern University Medical School, and the Cook County Graduate School of Medicine.

Arch Surg. 1963;87(6):916-930. doi:10.1001/archsurg.1963.01310180032008

We have previously reported on general factors influencing the incidence and mortality of 1,904 patients admitted to the Cook County Hospital with a proved acute perforation of a gastroduodenal ulcer1 and of 2,008 ulcer patients admitted to the same hospital for massively bleeding gastroduodenal ulcer.2 In other publications3,4 we commented on the signs and symptoms which influenced the prognosis of both of these two groups of patients and upon the laboratory findings in acute perforated gastroduodenal ulcer.5 In this paper, we wish to report the laboratory findings of the 2,008 ulcer patients treated for massive bleeding between 1936 and 1955.

Only those cases were accepted whose history gave overt evidence of copious intestinal bleeding and which showed radiologic, gastroscopic, operative, or necropsy evidence of a peptic lesion of the stomach or duodenum. We defined massive hemorrhage as: (1) a reduction of blood volume by one third