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January 1964

Limb ReplantationIII. Long-Term Evaluation

Author Affiliations

Research Fellow of the Gustavus and Louise Pfeiffer Research Foundation (Dr. Eiken).; Neurological Unit, Boston City Hospital, supported by grant No. NB 02613-03, National Institute of Neurological Diseases and Blindness. (Dr. Mayer).; From the Department of Surgery, Tufts University School of Medicine, and the First (Tufts) Surgical Service at the Boston City Hospital.

Arch Surg. 1964;88(1):66-77. doi:10.1001/archsurg.1964.01310190068008

In previous studies, attention has been given to the technique1 and pathophysiology of limb replantation2 in the experimental animal. Although many investigators have successfully replanted hind limbs in animals,3-5 detailed reports of the late results of replantation are incomplete. Lapchinsky6 reported his experience with replantation of preserved canine limbs. Long-term evaluation of these dogs, including electromyographic determinations, revealed remarkable functional regeneration in transected limbs. The present report deals with the ultimate condition and functional capacity of successfully replanted canine hind limbs with special reference to more detailed examination of the neuromuscular system.

Material and Methods  Fifteen adult dogs, which had the left hind limb amputated at midthigh and immediately replanted, were followed for periods of 3 to 29 months. These animals were examined during this period and at the time of sacrifice with reference to the neuromuscular, circulatory, and osseous systems. The neuromuscular system was examined

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