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February 1964

Benign Leiomyomas Of the DuodenumA Report of Three Cases and a Review of the Literature

Arch Surg. 1964;88(2):308-313. doi:10.1001/archsurg.1964.01310200146031

Introduction  Benign tumors of the duodenum present a rare but challenging surgical problem.1,25,31,19,32 As with other benign tumors of the small intestine the leiomyoma has the greatest clinical significance. When a review of the world literature revealed but 46 duodenal leiomyomata, recent experience with three additional cases seemed worthy of reporting (see Table). Two of these cases were encountered in reviewing the operative records at the Cook County Hospital from 1956 to the present time. No cases were observed in the last 7,000 autopsies performed at this institution.

Historical Review  The first report of a leiomyoma of the duodenum was by Hoffmeister in 1935, exactly 100 years after Cruveilhier's original description of a benign duodenal tumor.20 Hoffmeister's patient underwent a local excision of a 1 cm tumor from the duodenal wall with primary closure of the duodenum and a gastroenterostomy. Two years later Le Bigot reported a duodenal