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March 1964

Chronic Occlusive Arterial Disease of Lower Extremity In Japan: With Special Reference to Buerger's Disease

Author Affiliations

From the Second Surgical Division, Okayama University Hospital, Japan.; Assistant Professor of Surgery, Okayama University, Japan (Dr. Inada).; Assistant in Surgery, Second Surgical Division Okayama University Hospital, Japan (Dr. Hayashi).

Arch Surg. 1964;88(3):454-460. doi:10.1001/archsurg.1964.01310210128022

Chronic occlusive disease of the peripheral arteries, although not so common as in the Western countries, is not rare in Japan. Until a decade ago, it was the general belief that there were two distinct types of occlusive arterial disease, namely, Buerger's disease and arteriosclerosis obliterans. As a result of recent careful morphologic and angiographic studies there has been a reevaluation of the entity known generally as Buerger's disease. Several American workers have suggested that Buerger's disease is not a definite clinical entity and now consider arteriosclerosis as the principal cause of chronic occlusive disease of peripheral arteries.*

The purpose of this paper is to describe our experiences with these diseases in Japan and to discuss the entity known as Buerger's disease based on a long follow-up and on angiographic studies in two study groups.

I Follow-up Study (Group A)  During the years 1945 to 1959, a total of 124

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