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May 1964

Leiomyomas of the Gastrointestinal Tract

Arch Surg. 1964;88(5):892-896. doi:10.1001/archsurg.1964.01310230168031

Leiomyomas of the gastrointestinal tract are relatively rare lesions and form an unusual and interesting group of neoplasms. They may originate from any smooth muscle fiber in the gastrointestinal tract and have been recorded at all levels.

Many are well circumscribed, seemingly encapsulated, pinpoint to pea-sized nodules and as such are of little clinical importance. They are more easily recognized by palpation than any other way. When somewhat larger, but still asymptomatic, they may be found by accident during an operation and possibly confuse the diagnostic issue.

Clinical features of leiomyoma depend largely upon their individual growth characteristics. Many tumors may grow away from the lumen, protrude from the serosal surface, and present as a mass. Others may grow into the lumen and present with signs and symptoms of any tumor mass projecting into a hollow viscus. The normal mucosa may be thinned out and easily traumatized, and ulceration may

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