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December 1964

Gastric Freezing: A Clinical Evaluation

Author Affiliations

University of Colorado School of Medicine, Associate Clinical Professor of Medicine (Dr. Kauvar); Resident in Medicine (Dr. Karsh); Instructor of Surgery (Dr. Hermann).; From the departments of gastroenterology and surgery, General Rose Memorial Hospital, Veterans Administration Hospital, and the University of Colorado School of Medicine.

Arch Surg. 1964;89(6):985-988. doi:10.1001/archsurg.1964.01320060053010

Introduction  Freezing the mucosa of the stomach has been reported to achieve a physiologic gastrectomy with a profound depression of gastric secretion.1 Initial studies reported this to be a safe and effective method of treatment. However, subsequent investigations have not seemed to substantiate these early good reports, and various editorials and clinical studies have interjected serious reservations about this new mode of therapy.2-5 This study was initiated in March of 1962. A total of 21 patients had a peptic ulcer diathesis treated by gastric freezing. Prior to undertaking clinical work, the investigators spent sufficient time in the dog laboratory to thoroughly familiarize themselves with all the technical aspects of gastric freezing.

Selection of Patients.  —The patients ranged in age from 24 to 74 years. There were 19 males and two females. Some patients had the possibility of gastric freezing suggested to them as a means of controlling their

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