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January 1965

Pathologic Fractures of Femur Treated at Mayo Clinic (1950-1959): Clinicopathologic Study

Author Affiliations

From the Mayo Clinic and Mayo Foundation. Fellow in Orthopedic Surgery (Dr. Lynch); Section of Orthopedic Surgery (Dr. Sullivan); Section of Surgical Pathology (Dr. Dahlin).

Arch Surg. 1965;90(1):127-132. doi:10.1001/archsurg.1965.01320070129028

A STUDY was undertaken to determine the specific causes, methods of treatment, and the end results of all pathologic fractures of the femur treated at the Mayo Clinic over a ten-year period. Medical records and corresponding roentgenograms were reviewed. In those instances in which surgical specimens were obtained, the diagnosis was verified by reexamination of the microscopic sections. By means of return visits, personal communications, and letters of inquiry, we were able to determine the post-treatment course.

Our investigation disclosed 108 cases. Because of insufficient information, two were deleted, leaving a total of 106 cases of pathologic fracture of the femur for our study. In the interest of simplification, we have chosen to divide these cases into the following six groups which are indicative of the cause of the fracture: group 1, metastatic tumor; group 2, primary malignancy; group 3, lymphoma and leukemia; group 4, benign tumors and cysts; group

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