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February 1965

Intravenous Radioportography: Screening Procedure for Patients With Portal Hypertension

Author Affiliations

From the Surgical Department and the Radioisotope Unit Freie Universität Berlin.

Arch Surg. 1965;90(2):237-239. doi:10.1001/archsurg.1965.01320080061014

ROUTINE splenic portal venography is at present regarded as one of the outstanding contributions in the field of liver disease complicated by portal hypertension (Sherlock). The drawbacks of this procedure, splenic puncture, risk of bleeding, and injuries to neighboring organs are all too well known, so that routine application of the method, which was first described by Abeatici and Campi in 1951, has been delayed for a considerable period of time.

Subsequently, we report on our experience with a method of intravenous injection of isotopes and scintillation counting over the liver. This method was first described in 1962 (Grünert and Oeff) and seems qualified to replace routine splenoportography in patients with portal hypertension by selecting all patients with a patent portal vein.

Method  Between 10 and 50μc of hippurate I 131 diluted in 1 ml of saline or any other suitable γ-ray emitting isotope is injected intravenously. The resulting activity

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