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March 1965

Carcinoma of the Larynx: Results of Therapy in 209 Cases

Author Affiliations

From the departments of surgery and otolaryngology, The Johns Hopkins University School of Medicine and The Johns Hopkins Hospital, Baltimore. Instructor in Surgery (Dr. Baker), Instructor in Otolaryngology (Dr. Cherry).

Arch Surg. 1965;90(3):449-453. doi:10.1001/archsurg.1965.01320090127028

THE treatment of laryngeal carcinoma continues to be controversial. The disease presents a wide spectrum of anatomical involvement. Its response to irradiation and various forms of surgical excision is variable. The patient with a small intrinsic lesion is offered an excellent chance of cure by either limited surgical excision3 or irradiation.1 On the other hand, large extrinsic lesions with lymph node metastases are difficult to cure by either method.4 This problem is further complicated by the advantages of preserving the larynx versus the increased cure rate of total laryngectomy.

This study analyzes the treatment of laryngeal carcinoma at the Johns Hopkins Hospital. The records of all patients with a diagnosis of laryngeal carcinoma between 1950 and 1961 have been reviewed. Satisfactory clinical data and follow-up information have been obtained on 209 patients. The analysis has included the patient's age, sex, race, and presenting symptoms. Clinical staging was

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