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April 1965

Extramedullary Hematopoiesis Simulating Intrathoracic Tumor

Author Affiliations

From the Surgical Service, Saint Luke's Hospital. Associate Clinical Professor of Surgery (Dr. Condon) and Assistant Clinical Professor of Medicine (Dr. Safarik), University of Colorado School of Medicine; Professor of Clinical Pathology, Colorado State University (Dr. Elzi).

Arch Surg. 1965;90(4):643-648. doi:10.1001/archsurg.1965.01320100187027

THIS case warrants reporting and discussion because extramedullary (heterotopic) bone marrow in massive enough amounts to simulate tumor is being encountered intrathoracically with increasing frequency.

Report of Case  A 56-year-old white male of German extraction was first seen on Jan 12, 1964, after a routine chest x-ray (Fig 1 and 2) which revealed multiple bilateral, somewhat symmetrical, ovoid masses situated paravertebrally in the posterior mediastinum. He felt well and had no clinical complaints. His health had always been good, uninterrupted by serious illness or surgery. Initially he related no significant family history, and his 78-year-old mother and 79-year-old father were both alive and well.Clinical examination revealed no gross abnormalities other than an enlarged left axillary lymph node. Pertinent hematological examinations showed a hematocrit of 39%, hemoglobin of 14.6 gm/100 ml, red cell count of 4,710,000/cu mm, white cell count of 11,900/cu mm with a normal differential and corpuscular constants.

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