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August 1965

Studies on the Blood Vessels in Peptic Ulcer: "The Ulcer Vessel Nest"

Author Affiliations

From the Department of Surgery, College of Medicine, University of Iowa.

Arch Surg. 1965;91(2):221-227. doi:10.1001/archsurg.1965.01320140011003

THIS is a report of studies of the blood vessels associated with the peptic ulcer predisposition. The purpose of this paper is to discuss changes found in the vessels under the ulcer, to describe the "ulcer vessel nest," and to discuss some implications of these observations. These studies are an outgrowth of explorations with the stereo-operating microscope in studying tissues and relationships in their natural state.1

In early reports2,3 we described vascular formations of the lips ("microcherry," "glomerulus", "venous lake") which were found more often in persons with ulcer than in persons without ulcer. Later we reported4 alterations in the blood vessels of the stomach and duodenum ("ectasia," "vascular raspberry," "ulcer vessel nest") in gastric specimens removed from patients with ulcer. These changes were correlated with the findings in lip vessels and were also compared with findings in specimens derived from postmortem examination. We concluded that alterations

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