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August 1965

Hyperbaric Oxygenation in Surgery: Application to Organ Graft Survival

Author Affiliations

Professor of Surgery, University of Minnesota Medical School, Chief of Surgery, Hennepin County General Hospital (Dr. Hitchcock); Onan Family Professor of Surgery, University of Minnesota, Assistant Chief of Surgery, Hennepin County Hospital (Dr. Haglin).

Arch Surg. 1965;91(2):307-313. doi:10.1001/archsurg.1965.01320140097013

HYPERBARIC oxygenation is now a wellestablished research method in medicine and surgery. Recently a complex hyperbaric research facility was opened at the Hennepin County General Hospital in Minneapolis. Designed as four chambers, this unit includes a spherical operating room, 19 feet in diameter, which is ideal for the study of surgical problems under hyperbaric conditions (Fig 1, 2). During the first nine months of operation the chambers were used for 300 treatment cycles at a pressure of three atmospheres (atm) absolute (the pressure equal to 66 feet of depth in sea water). Maximum operating pressures are 7 atm absolute for one horizontal chamber and the entrance lock, and 4 atm absolute for the spherical operating room and the second horizontal chamber. The physical characteristics of the hyperbaric facility have been described in a recent publication which emphasizes the need for maximum safety of both design and operation of hyperbaric units.