DESPITE increasing success in intracardiac surgery in the young infant, mortality rates are still high. Among the difficulties inherent in such surgery, extracorporeal circulation in young, small individuals plays a prominent role. For this reason, experience with cardiopulmonary bypass in small animals is essential for successful intracardiac surgery in infants.
Several authors1,7 have reported experiences with extracorporeal circulation in the puppy, and mortality rates have been high. The use of the dog for such experiments has been criticized, and an impression has been created that high mortality rates are to be expected.3
This paper reports initial experiences in this laboratory with extracorporeal circulation in young puppies and suggests that such procedures can be undertaken with reasonable expectation of success.
Material and Methods
Mongrel puppies weighing 2.14 to 5.58 kg (4.7 to 12.3 lb) were anesthetized with intravenous pentobarbital (Nembutal), and positive pressure respiration was maintained with warmed, humidified
JENS G. ROSENKRANTZ, ROBERT MacMAHON, WARREN W. FROST, BRUCE C. PATON, HENRY SWAN. Extracorporeal Circulation in Puppies. Arch Surg. 1965;91(3):513–515. doi:10.1001/archsurg.1965.01320150143028