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January 1966

Primary Malignant Lymphoma of Colon or Appendix: Report of 27 Cases

Author Affiliations

From the Section of Surgical Pathology, Mayo Clinic and Mayo Foundation, and the Mayo Graduate School of Medicine, University of Minnesota.

Arch Surg. 1966;92(1):144-151. doi:10.1001/archsurg.1966.01320190146033

PRIMARY malignant lymphoma of the colon and appendix is rare. Reports on this subject are often confused and difficult to evaluate inasmuch as many authors have considered the entire gastrointestinal tract when discussing this type of neoplasm. In addition, in most instances, no attempt has been made to exclude patients with evidence of partial or generalized involvement of the reticulo-endothelial system. The problem is further compounded by the confusion that has existed concerning the classification of malignant neoplasms of the reticuloendothelial system.

This paper presents experiences with 27 carefully selected cases of primary malignant lymphoma of the colon (exclusive of the rectum) and appendix in patients who, at operation, manifested no evidence of spread beyond the confines of the colon, immediately adjacent ileum, or appendix and the immediate regional lymph nodes.

Background  Involvement of the gastrointestinal tract by malignant lymphoma has been recognized since the earliest description of the disease