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March 1966

Ruptured Tubal Pregnancy With Elevated Serum Amylase Levels

Author Affiliations

From the Department of Surgery, University of Cincinnati College of Medicine and Cincinnati General Hospital.

Arch Surg. 1966;92(3):397-398. doi:10.1001/archsurg.1966.01320210077015

HOWARD1 lists many diseases in which the serum amylase level may be elevated including ruptured tubal pregnancy.

A search of the literature disclosed a single case report2 of ruptured ectopic pregnancy with elevated serum amylase levels. It is that of a woman, aged 22 years, with acute abdominal pain, abdominal tenderness and rigidity, and a serum amylase level of 1,600 Somogyi units (normal is less than 200 units). A laparotomy was performed and a ruptured tubal pregnancy removed. The pancreas, gallbladder, and liver were normal. The next day the serum amylase was 1,680 units; 14 days later, 360 units; one year later, 300 units; and two years later, 110 units. Cholecystogram, glucose tolerance test, and mumps complement fixation test were normal.

We recently treated a similar case and think it worthwhile reporting, for the abnormal levels of serum amylase led to delay in making the correct diagnosis.