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August 1966

Primary Cancer of the Liver in ChildhoodA Review With Emphasis on Treatment and Survival

Arch Surg. 1966;93(2):355-359. doi:10.1001/archsurg.1966.01330020147025

PRIMARY liver cancer, whether in the adult or child, is generally fatal. A few isolated reports of survival following surgical excision have appeared over the past few years to offer some encouragement in the management of these tumors in children. The experience at the University of Texas Medical Branch with hepatocarcinoma was reviewed to determine if there are characteristics of the childhood neoplasm that differentiate it from the adult counterpart. It shows that primary hepatic cancer in childhood is quite different from the adult neoplasm.

In the past 15 years, six children with hepatic carcinoma were treated at the University of Texas Medical Branch. Table 1 summarizes the data on these patients. Diagnosis in the first four patients was established by liver biopsy, and no definite treatment was attempted. The fifth case was an adenocarcinoma of the liver developing in a child with congenital biliary atresia. The sixth patient emphasizes

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