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October 1966

Disposable Bubble Oxygenator: Experimental Studies of Its Performance

Author Affiliations

From the Division of Thoracic and Cardiovascular Surgery, Washington University School of Medicine, St. Louis.

Arch Surg. 1966;93(4):660-663. doi:10.1001/archsurg.1966.01330040124024

AN EVALUATION of the disposable bubble oxygenator (Travenol U-310) has been done under controlled conditions to determine the circumstances under which optimum performance might be expected and to define the margin of safety which this oxygenator affords. Blood of any desired gas composition was obtained by recirculation through a stationary screen oxygenator (Mayo-Gibbon) using various gas mixtures in the chamber. The blood was then passed a single time through the bubble oxygenator and changes in a particular parameter measured. Three parameters have been studied: (1) the effect of varying the gas flow rate to the oxygenator, (2) the effect of blood flow on the ability of the oxygenator to oxygenate blood, and (3) the ability of the oxygenator to remove carbon dioxide.

Experimental Design  Preliminary to the experimental determination, it was necessary to have information on the efficiency of the screen (control) oxygenator. In these experiments efficiency was defined in

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