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June 1967

Hyperglycemia After Gastrectomy as a Prediabetic State: Clinical Study of 100 Postgastrectomy Patients

Author Affiliations

Kyoto, Japan
From the Surgical Department, Japan Baptist Hospital, Kyoto.

Arch Surg. 1967;94(6):836-840. doi:10.1001/archsurg.1967.01330120090016

OXYHYPERGLYCEMIA, which was first reported by Lawrence1 (1936) as a symptomless glycosuria, has recently been implicated as a prediabetic state.2

As already pointed out by Lawrence, oxyhyperglycemia often occurs when there is immediate absorption of glucose from the intestine, especially after gastroenterostomy. However, the incidence and exact nature of oxyhyperglycemia after gastrectomy and its relationship to the prediabetic state are still unknown.

The incidence of oxyhyperglycemia in relation to disease, type of surgery, and age was investigated in 100 patients who had undergone gastrectomy.

Materials, Methods, and Criteria  The glucose tolerance test (GTT) was administered to 100 postgastrectomy patients, of whom 96 had been operated on at this hospital and 4 had received gastrectomy elsewhere and visited our hospital because of glycosuria.Fifty grams of glucose in 325 cc of water was given orally after venous blood had been drawn for fasting blood glucose determinations. Blood glucoses were