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February 1968

Carbon Monoxide Poisoning: Treatment by Hyperbaric Oxygenation

Author Affiliations

New Orleans
From the Department of Surgery, Tulane University School of Medicine (Dr. Kokame), and the Department of Pediatrics, Ochsner Clinic (Dr. Shuler), New Orleans. Dr. Kokame is currently at 181 S Kukui St, Honolulu.

Arch Surg. 1968;96(2):211-215. doi:10.1001/archsurg.1968.01330200049007

IN clinical applications, Smith1 confirmed theoretic expectations of hyperbaric oxygenation in treatment of patients with carbon monoxide intoxication. Of 70 patients with carbon monoxide poisoning treated with oxygen under pressure by Smith and Sharp,2 only two died. Both had been slowly poisoned by gas over intervals of at least eight hours.

Carbon monoxide occurs in the home through leakage of manufactured gas from open burners and defective appliances and from incomplete oxidation of commercial gas products. Carbon monoxide fumes may be found in the coal mining and steel industry, in gas manufacturing, and in use of explosives in closed places, as well as in smoke, in enclosed spaces that have been painted with oil paints, and in the exhaust of internal combustion engines. Carbon monoxide poisoning from motor exhaust gas in closed garages has been responsible for many suicides and accidental deaths.

Two brothers with acute carbon monoxide