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June 1968

Radiation Hepatitis

Author Affiliations

From the departments of surgery (Drs. Lansing and Davis) and radiology (Dr. Brizel), University of Louisville School of Medicine, Louisville.

Arch Surg. 1968;96(6):878-882. doi:10.1001/archsurg.1968.01330240024006

IN RECENT years, due largely to improved equipment and techniques, the vigorous radiotherapeutic treatment of malignancy in and about the liver has become desirable under appropriate circumstances. Until recently, the liver was considered nearly radioresistant, and modern textbooks continue to propagate this misconception based on animal experimentation performed prior to World War II.1,2 Therefore, we are reporting an unusual case of jaundice mimicking the Budd-Chiari syndrome in a patient who received radiation therapy following surgical removal of a hypernephroma and its extension into the vena cava. It is important because of its rarity, the lack of awareness of the condition by surgeons, and the availability of the extensive diagnostic measures that were performed.

Report of a Case  A 47-year-old woman was found to have a right renal tumor in the course of investigation of back pain secondary to an old thoracolumbar disc disease. On March 4, 1966, she underwent

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