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October 1968

Effect of Cholecystectomy on the Biliary Ducts in the Dog

Author Affiliations

Rochester, Minn
From the sections of physiology (Dr. Wakim), surgical pathology (Dr. Soule), and surgery (Dr. Ferris), Mayo Clinic and Mayo Foundation, and the Mayo Graduate School of Medicine, University of Minnesota (Dr. Mahour), Rochester.

Arch Surg. 1968;97(4):570-574. doi:10.1001/archsurg.1968.01340040066011

ALTHOUGH it has been stated that dilatation of the common bile duct occurs as a compensatory phenomenon after cholecystectomy,1-6 our autopsy findings7 and cholangiographic studies by others8-12 do not substantiate this in man. We therefore investigated experimentally in the dog the effect of cholecystectomy on the biliary ducts.

Materials and Methods  The gallbladders were removed aseptically (with general anesthesia) from 48 normal mongrel dogs which weighed 11 to 16 kg (24.2 to 35.3 lb). At operation, the condition of the liver and extrahepatic bile ducts was studied carefully. The dogs were divided into four groups, according to which one of the following additional procedures was used:Group 1 (14 dogs).—The whole cystic duct was removed by ligating it flush with the common bile duct.Group 2 (13 dogs).—The whole cystic duct was retained.Group 3 (10 dogs).—The whole cystic duct was removed by ligating