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January 1969

Hepatic Lobectomy for Hepatoblastoma in Infants and Children

Author Affiliations

From the Department of Surgery of the College of Medicine, The University of Cincinnati, and the Surgical Service of The Children's Hospital, Cincinnati.

Arch Surg. 1969;98(1):1-7. doi:10.1001/archsurg.1969.01340070019001

The necessity for an aggressive approach in the treatment of hepatoblastoma is receiving increasing emphasis throughout the surgical world. Currently available surgical techniques and more knowledgeable appreciation of the postoperative physiological disturbances have made major hepatic resections possible in children with minimal operative risks. As a result, any infant or child with a possible hepatoblastoma deserves surgical exploration as the only hope of survival.

The long term follow-up of patients undergoing major hepatic resections for benign lesions1,2 has proven to be uniformly gratifying. The course of hepatoblastoma, however, even after apparently adequate resection, has characteristically been one of local recurrence, widespread metastases and death. Only in recent years have the first five year survivals been reported.

In the period of five years since September 1961, five children have undergone major hepatic resections for hepatoblastoma in the Department of Surgery of the Children's Hospital and the University of Cincinnati. These