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March 1969

Combined Leukemia, Carcinoma, and Hyperplasia of the Prostate

Author Affiliations

From the Department of Surgery, Case-Western Reserve University, and the Veterans Administration Hospital, Cleveland.

Arch Surg. 1969;98(3):365-366. doi:10.1001/archsurg.1969.01340090141026

The prostate gland is uncommonly invaded by chronic lymphatic leukemia. Prostate glands so involved, obtained surgically or during necropsy, have frequently presented histologically combined manifestations of adenomatous hyperplasia plus diffuse and nodular leukemic infiltration.1 The possibility of such an infiltration is always present when symptoms of prostatism develop in a patient with leukemia. Rarely, on the other hand, is the prostate involved with both chronic leukemic infiltration and primary adenocarcinoma. This report describes a case in which the prostate was the seat of all these diseases, ie, benign prostatic hypertrophy, adenocarcinoma, and leukemia.

Report of a Case  A 77-year-old Negro was admitted to the Urology Service, Veterans Administration Hospital, Cleveland, on Dec 21, 1966, for evaluation of symptoms of prostatism, manifested by frequency, hesitancy, and dribbling. The patient had had a transurethral resection of benign prostatic tissue for similar symptoms four years previously. Two years prior to the present