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August 1969

Lobular Carcinoma of the Breast-1969: A Therapeutic Proposal

Author Affiliations

Torrance, Calif; Los Angeles
From the departments of surgery and radiology, Harbor General Hospital, Torrance, Calif, and the University of California at Los Angeles (Drs. Benfield and Fingerhut) and the Department of Pathology, Los Angeles County General Hospital, and the University of Southern California, Los Angeles (Dr. Warner).

Arch Surg. 1969;99(2):129-131. doi:10.1001/archsurg.1969.01340140001001

In recent years the diagnosis of lobular carcinoma of the breast has been made with increasing frequency. The in situ form as well as the infiltrative variety are now well-recognized, and it is clearly established that both are true cancers.1 Because there are features of lobular breast cancer which distinguish it from the common infiltrating ductal carcinoma, we suggested a therapeutic approach in 1965 when fewer than 40 patients with in situ lobular carcinoma had been reported.2 Now that the experience with almost 500 reported patients with lobular carcinoma has been reviewed,3 the natural history of the disease is well enough known to justify supporting and extending these therapeutic recommendations. Our purpose is to present the treatment regimen we are currently following.

In Situ Lobular Carcinoma  This neoplasm is often not a tumor in that the palpable mass for which the biopsy was undertaken proves to be