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December 1969

Mitral Valve Replacement With Stented Aortic Homograft: A Hemodynamic Evaluation

Author Affiliations

Rochester, Minn
From the sections of medicine (Dr. Frye) and surgery (Dr. Ellis), Mayo Clinic and Foundation, and the Mayo Graduate School of Medicine (University of Minnesota) (Dr. Dunlap), Rochester, Minn.

Arch Surg. 1969;99(6):821-824. doi:10.1001/archsurg.1969.01340180145027

Extensive data are available defining the hemodynamic improvement that occurs when the mitral valve is replaced with a mechanical prosthetic device.1-6 Evaluation of long-term clinical results with these mechanical prosthetic devices, however, has revealed disturbingly high late morbidity and mortality from fatal or disabling thromboembolic complications.7,8 Because of these problems, interest developed in the use of the aortic valve homograft as a prosthesis for mitral valve replacement. It also was thought that hemodynamics in the immediate postoperative period might be better with a homograft than with a prosthesis if the presence of a cage and ball interfered with left ventricular performance. The present study, therefore, was undertaken to examine the hemodynamic state of ten patients in the immediate postoperative period after replacement of the mitral valve with a stented aortic valve homograft.

Material  Ten patients were studied before, on the first three days after, and nine days to

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