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March 1970

Primary Carcinoma of the Gallbladder

Arch Surg. 1970;100(3):232-235. doi:10.1001/archsurg.1970.01340210008003

This paper is a review of our experience with primary carcinoma of the gallbladder at the Akron City Hospital. The records of all patients with cancer of the gallbladder in the years 1958 to 1968 were studied. Forty-one cases were found among 4,000 cholecystectomies, an incidence of 1% carcinoma of the gallbladder (Fig 1). This incidence is in close agreement with the collective review made by Arminski.1 He found 569 carcinomas of the gallbladder in 46,480 operations on the biliary tract, an incidence of 1.12%.

Numerous reports from the various clinics have revealed little change in the overall picture of carcinoma of the gallbladder. The five-year survival rate for patients with the disease has been uniformly poor, varying from 1% to 6%.1-3 In this country, it is the fifth most frequent type of carcinoma of the gastrointestinal tract and causes approximately 6,500 deaths annually.4

Etiology  Cholelithiasis, cholecystitis,

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