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May 1970

Isolated Splenic Vein Occlusion: Review of Literature and Report of an Additional Case

Author Affiliations

Charleston, SC
From the Department of Surgery, Medical College of South Carolina, and Charleston Veterans Administration Hospital, Charleston, SC. Dr. Sutton is now at the Vanderbilt University School of Medicine and the Veterans Administration Hospital, Nashville, Tenn.

Arch Surg. 1970;100(5):623-626. doi:10.1001/archsurg.1970.01340230089024

In 1866, Gretsel described a syndrome consisting of primary splenomegaly, secondary anemia, and chronicity. Griessinger termed this splenic anemia.1

In 1894, Banti isolated his syndrome from this broad entity.1 Banti defined three clinical features: (1) a period lasting from three to five years and characterized by splenomegaly and anemia; (2) a short period characterized by hepatomegaly and oliguria; and (3) a final period lasting one to two years and characterized by ascites and a small liver. He also noted that the syndrome was frequently associated with hemorrhages from the mouth and bowel, an icteric skin hue (without true icterus), and a secondary anemia distinguished by leukopenia and relative lymphocytosis.

Pathologically, Banti noted that this entity demonstrated (1) endophlebitis and calcification of the splenic vein; (2) splenic reticular fibrosis with narrowing of the splenic vein and capsular thickening; (3) presence of cirrhosis of the liver; and (4) finding of

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