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July 1970

Atherosclerotic Change Occurring in an Autogenous Venous Arterial Graft

Author Affiliations

Rochester, NY
From the Department of Surgery, University of Rochester School of Medicine and Dentistry, Rochester, NY. Dr. Beebe is now at the University of Maryland, Baltimore.

Arch Surg. 1970;101(1):85-88. doi:10.1001/archsurg.1970.01340250087019

Autogenous venous grafts are widely accepted as the method of choice for treatment of femoropopliteal occlusive disease because of their generally satisfactory long-term patency rates.1,2 This long-term durability of vein grafts may in part be due to their resistance to atheromatous degeneration. On occasions when vein grafts have been recovered from patients,3-7 such changes have not usually been found. Experimental reports have differed widely,8,9 but when precise criteria are followed, vein grafts appear resistant to the development of atherosclerosis.10 It is extremely rare to encounter true atherosclerotic change occurring in vein grafts implanted clinically. This is indicated by the fact that the following case is, so far as we know, only the second such instance reported.

Report of a Case  A 36-year-old factory worker (unit No. 1-57-87) entered Strong Memorial Hospital for the first time on June 7, 1955, with an 8 month history of progressive,