Polyglycolic acid sutures were compared experimentally with catgut, silk, and Dacron. The sutures were implanted in the muscles of rabbits and the specimens recovered at intervals up to eight months. Polyglycolic acid sutures lost a third of their original strength in one week and about 80% by two weeks. Catgut lost strength more slowly. The tissue reaction to polyglycolic acid was not marked and consisted mainly in a cellular infiltrate between the strands. Generally, polyglycolic acid was absorbed more rapidly than catgut.
Postlethwait RW. Polyglycolic Acid Surgical Suture: R. W. Postlethwait, MD, Durham, NC. Arch Surg. 1970;101(4):489–494. doi:10.1001/archsurg.1970.01340280041011
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