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November 1970

Experimental Massive Intestinal Resection: Comparison of Surgical Measures and Spontaneous Adaptation

Author Affiliations

New York
From the Division of Surgery, Division of Medicine and Department of Gastroenterology, Montefiore Hospital and Medical Center, and the Albert Einstein College of Medicine, Bronx, New York.

Arch Surg. 1970;101(5):599-604. doi:10.1001/archsurg.1970.01340290055012

In a comparison of dogs with 75% and 80% intestinal resection with a reversed intestinal segment pouch, the reversed ileal segment and resection alone failed to reveal short-term difference in fecal fat excretion in the three groups on a controlled diet. In animals with long-term follow-up fat excretion studies, there was persistent steatorrhea with the reversed intestinal segment pouch and reversed ileal segments, compared to the controls. A better weight pattern, fat absorption, and survival was observed in the dogs with intestinal resection alone. In view of the relatively good recovery and nutritional status of dogs undergoing 75% and 80% intestinal resection coupled with the available experimental and clinical reports, it appears that long-term value of therapy by reversed intestinal segments or other adjunctive surgical procedures for extensive small-bowel resections is not yet established.