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December 1970

Experimental Atherosclerosis in Autogenous Venous Grafts

Author Affiliations

Nashville, Tenn
From the S. R. Light Laboratory for Surgical Research, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tenn.

Arch Surg. 1970;101(6):677-682. doi:10.1001/archsurg.1970.01340300033007

In this experimental study, autogenous venous grafts implanted in the aorta and iliac and femoral arteries of dogs with hypercholesterolemia, induced by a standardized atherogenic regimen, developed diffusely severe atheroma and appeared to be even more susceptible to atheroma than autogenous aortic grafts, Dacron tubes, or the undisturbed arteries of the host.

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