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January 1971

The Dumping Syndrome: Experimental Studies on Pathogenesis

Author Affiliations

Yokohama, Japan
From the Department of Surgery, Yokohama University School of Medicine, Yokohama, Japan.

Arch Surg. 1971;102(1):40-42. doi:10.1001/archsurg.1971.01350010042010

Hyperosmolar glucose (50%) was introduced into the exteriorized ileum of rats and into the duodenum of dogs. Direct observations of the mesenteric microcirculation showed venous stagnation and opening of arteriovenous shunts. Portal venous oxygen levels increased and oxygen consumption in the portal area decreased. The theoretical relevance of these changes to the dumping syndrome is described.