Following full-thickness excision of flank skin in rabbits, omental microvascular dilatation was noted for a brief period, following which the vessels returned to pretrauma size. If a 0.4% body surface area (BSA) full-thickness contact burn was immediately excised, a change in the distant microcirculation similar to that seen with excision of skin alone was observed. If after the burn excision was not done the changes proceeded to be maximal at 30 minutes (venules) to 40 minutes (arterioles) and resolved by 60 minutes postburn. Application of a second challenge burn of the same size at 40 minutes postburn failed to prolong the recovery phase. Challenge with a burn averaging 0.7% BSA was associated with arteriolar and venular dilatation; but in no instance was there recovery of preburn venular size during the 90 minutes of postburn observation.
Jelenko C, Jennings WD, O'Kelley WR, Byrd HC. Threshold Burning Effects on Distant Microcirculation: I. Preliminary Observations. Arch Surg. 1971;102(6):617–625. doi:10.1001/archsurg.1971.01350060081025
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