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April 1972

Multiple Valve Replacement: An Analysis of Early and Late Results

Author Affiliations

From the departments of surgery, North-western University (Chicago) Medical School (Drs. Midell and DeBoer) and Chicago Wesley Memorial Hospital (Dr. DeBoer).

Arch Surg. 1972;104(4):471-476. doi:10.1001/archsurg.1972.04180040085015

The clinical results achieved with 91 patients who underwent multiple valve replacement showed that early hospital mortality was 12%. Triple valve replacement was associated with the highest mortality (25%), followed by mitral and tricuspid valve replacement (17%). Late mortality was 11%. Mitral and tricuspid valve replacement had the highest late mortality (29%). Congestive heart failure or low cardiac output was the highest single cause of early and late mortality (nine patients or 9%). Cerebral thromboembolic complications occurred in nine patients; four proved to be fatal. In addition, one patient died of a gastrointestinal tract hemorrhage due to profound hypoprothrombinemia. Long-term results indicated highly satisfactory rehabilitations in over 95% of those patients surviving for follow-up. The long-term results in multiple valve replacement now approach those already seen in single valve replacement.

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