[Skip to Navigation]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
August 1972

An Endoscopic Test for Completeness of Vagotomy

Author Affiliations

From the Department of Surgery, the Abraham Lincoln School of Medicine, University of Illinois at the Medical Center, Chicago. Dr. Kusakari is a visiting research associate from Tokyo, and Dr. Gillison is a visiting research associate from Sheffield, England.

Arch Surg. 1972;105(2):386-391. doi:10.1001/archsurg.1972.04180080230039

After application of Congo red dye to the gastric mucosa, the change in color from red to black can be observed by endoscopy at a pH below 3.0, indicating acid production.

In 13 dogs, the time required for complete color change in the parietal cell area was compared preoperatively, after anterior or posterior vagotomy, and following total vagotomy. (1) The interval for complete color change was significantly prolonged in animals with complete vagotomy compared to that in those with no vagotomy. (2) The Congo red test correlated completely with the Hollander test in showing the completeness of vagotomy.

Identical results were found in five patients who had had incomplete vagotomy previously. Furthermore, the site of the intact vagal branch could be localized with the method.